TS-OW TYPE

cGMP TERMINAL STERILIZERS

TS-OW TYPE

cGMP TERMINAL STERILIZERS

These sterilizers are fitted with a high-flow water recirculation system, consisting of centrifugal pumps and “double-head multitube” heat exchangers. This system uses water (WFI or PW) as a means of transferring heat to warm up, sterilize and cool down the load. It guarantees an optimal heat distribution throughout the entire sterilization phase, with a temperature deviation of less than ±1°C. This method enables faster cycles, although the treated product remains damp. Nevertheless, it is often chosen for its simplicity, cost-effectiveness and ease of validation.

LIQUIDS

OVERHEATED WATER

105°C – 121°C

Process features
Additional information

These sterilizers feature a high-flow water recirculation system, thanks to the centrifugal pumps and “double-head multitube” heat exchangers which allow a “water” medium (WFI or PW) to be used as a means of transferring heat to warm up, sterilize and cool down the load. The system ensures optimum heat distribution throughout the entire sterilization phase (temperature deviation less than ± 1°C). This process method includes faster cycles but the treated product comes out still damp. It is, however, still the preferred method in most case due to its simplicity, cost-effectiveness and ease of validation.

Circular cross-section sterilization chamber with square or rectangular hatches (doors).
The chamber of the TS OW model has a single wall (no jacket).
Reinforcements are welded onto the outside of the chamber to ensure stable operating conditions.
The chamber is placed on a base designed to evenly distribute the weight on the floor.
The loading cart-insertion and removal guides are placed on the bottom of the chamber; they are also height-adjustable.
The bottom of the chamber converges towards the drain sump to facilitate the condensation drain.
Two 2” tri-clamp ferrules are welded to the chamber for validation purposes (temperature uniformity mapping and pressure tests).
All of the chamber’s internal surfaces are mechanically polished and then undergo chemical degreasing, pickling and passivation treatments. Surface finish ≤ 0.35 micron.
The chamber can be installed at floor level or in a pit (depending on the size).