The future of biologics how technology is revolutionizing pharmaceutical production

Biologic drugs represent one of the most promising frontiers of modern medicine — advanced therapies that act at a molecular level to treat diseases once considered untreatable. Yet, their production is complex and requires absolute precision. In this evolving landscape, process technology becomes the key enabler to ensure safety, quality, and scalability.

The challenges of biologics manufacturing

Unlike traditional chemical drugs, biologics are highly sensitive to their production environment. Temperature, contamination, shear stress, and environmental variations can compromise their structure and activity. This makes it essential to rely on highly controlled processes, sophisticated purification systems, and flawlessly sterile environments.

In this context, advanced technologies for washing, decontamination, sterilization, and depyrogenation play a crucial role in ensuring that every component — from bioreactors to filling lines — remains compliant and contamination-free.

Key technologies shaping the future

Advanced washing and disinfection systems

Automated washing and disinfection processes with continuous monitoring of critical parameters ensure that surfaces are completely free from biological or chemical residues. LAST Technology’s washing systems minimize the risk of cross-contamination and optimize operational efficiency.
Learn more about Washing & Disinfection Solutions

Flexible sterilization solutions

For biologics, sterilization is a delicate phase — microbial reduction must be achieved without compromising sensitive components. LAST Technology’s customized sterilization systems, including saturated steam autoclaves, deliver flexibility and full compliance with GMP/GLP standards.
Explore our Sterilization Solutions

Depyrogenation for absolute purity

Endotoxins are among the most critical risks in biologics production, especially for injectable formulations. LAST Technology’s high-temperature depyrogenation systems ensure complete removal of pyrogens, guaranteeing the highest safety standards.
Discover our Depyrogenation Systems

Combined processes and integrated systems

A key trend in modern pharma manufacturing is the integration of multiple processes — washing, sterilization, and decontamination — into one controlled workflow. LAST Technology’s combined process solutions help reduce footprint, energy consumption, and downtime while improving overall process efficiency.
Learn more about our Combined Processes

Real benefits quality, efficiency, and sustainability

• Improved batch consistency and reproducibility
• Reduced cross-contamination risk
• Shorter setup and changeover times
• Lower energy and resource consumption (water, steam, reagents)
• Enhanced data traceability and regulatory compliance

Toward a predictive and adaptive future

The adoption of intelligent systems, advanced sensors, automation, and predictive algorithms is driving biologics manufacturing toward more adaptive and resilient models. The future will bring self-adjusting lines, automated corrections, and predictive maintenance — all focused on reliability and precision.

LAST Technology supporting the biologics industry

At LAST Technology, we believe that innovation must translate into tangible, reliable solutions. Our machines and process technologies are designed to meet the demanding needs of biologics production — today and in the future.

If your facility is planning or upgrading biologics manufacturing lines, contact us. We’ll guide you toward the most efficient solutions — from safe washing to precise sterilization and fully integrated systems.